Panama City is the easy start: a skyline on the Pacific, the restored streets of Casco Viejo, and the canal locks at Miraflores 15 minutes from downtown. A short flight away lie the Guna Yala islands on the Caribbean, the coffee highlands of Boquete and the quiet islands of the Gulf of Chiriquí.
It suits travellers who have done Costa Rica and want somewhere less visited. We plan three nights in the city, then two or three contrasting stays.
The caveat is that there are no direct flights from the UK, and outside Panama City and a handful of island lodges, hotels are simpler. The Pacific side is dry from about December to April; the Caribbean is wetter all year.