The USA rewards focus. A fortnight can cover the canyons of southern Utah and northern Arizona, or Yellowstone and the Tetons, or New York followed by a week of New England back roads. It cannot comfortably cover all three.
We plan around the national parks, which are the reason most of our travellers go. Lodges inside the parks put you at the viewpoints at dawn, before the day visitors arrive.
The honest caveats: distances are long, summer crowds at the big parks are real, and a dinner bill carries sales tax and a tip that is expected, not optional. Two nights at each stop makes it all calmer.